姓名：樊爱萍
职称/职务：教授，博士生导师，新疆大学药学院副院长
专业：药物分析学
研究方向：
（1）化学发光、荧光分析新方法在药物分析、核酸、肿瘤标志物及蛋白酶检测中的应用
（2）超高灵敏度的免疫层析分析技术的开发
（3）纳米酶催化活性的研究及应用
邮箱：fanap@xju.edu.cn
办公室：新疆大学博达校区药物研究所306室
个人经历
学习经历：
2003.09-2009.06，复旦大学药学院，药剂学，博士（导师：卢建忠教授）
1999.09-2003.06，复旦大学药学院，药学，学士
工作经历：
2020.07-至今,天津大学，药物科学与技术学院，教授
2015.08-2016.08,麻省大学阿默赫斯特分校，化学系，访问学者，合作导师：Vincent Rotello教授
2013.07-2020.06,天津大学，药物科学与技术学院，副教授
2009.07-2013.06,天津大学，药物科学与技术学院，讲师
主讲课程
本科生课程：
2017年-至今，基础化学实验 （全英文课程）
2010-2018，药物分析
研究生课程：
2021年-至今，化学发光分析及其在药物分析中的应用（全英文课程）
2017-2020，基于纳米材料的生物传感 （全英文课程）
2010-2015，药物仪器分析
获得的荣誉
2025年，天津大学工会积极分子
2021年，天津大学教师教学创新大赛正高组 优秀奖
2021年，天津大学优秀青年教师
2021年，天津大学工会积极分子
2020年，国家一流本科课程（排名第二）
2018年，国家教学成果奖二等奖（排名十一）
2013年，天津大学北洋青年骨干教师
2012年，天津大学三八红旗手
2011年，天津大学毕业生就业工作先进个人
2009年，复旦大学优秀博士论文
2009年，上海市优秀毕业生
主持科研项目
1.内蒙古科技计划项目：术后认知功能障碍生物标志物快速检测方法的开发与应用(2025KJHZ0013)，2025-2028，子课题主持。
2.横向项目：基质金属蛋白酶检测方法的开发，2024-2026，主持。
3.国家重点基础研究发展计划，分子基功能碳材料新型拓扑结构的基础与前沿研究（2015CB856500），2015-2019，子课题参与。
4.国家自然科学基金面上项目，氧化石墨烯脂质体的制备及其在化学发光生物分析中的应用(21475094)，2015-2018，主持。
5.天津应用基础与前沿技术研究计划，免洗涤步骤的三指标肿瘤血清标志物同时检测新技术，2015-2018，主持。
6.国家自然科学基金青年基金，基于核酸适体的超高灵敏度化学发光蛋白质分析新技术的研究(21105071)，2012-2014，主持。
7.中国高等教育博士点专项科研基金，超高灵敏度的蛋白质化学发光分析(20110032120079)，2012-2014，主持。
8.天津大学北洋青年骨干教师计划，化学发光和生物发光，2013-2014，主持。
9.天津大学自主创新基金，基于脂质体的化学发光免疫分析，2010-2011，主持。
10.天津大学青年教师培养基金，基于发夹结构的乙型肝炎病毒诊断技术，2011-2011，主持。
社会工作
中国分析测试学会分析药学专委会委员
代表性研究成果
1.Li,S.;Hong,S.;Sun,Y.;Liu,X.;Zhou,P.; Zhang,Z.; Zhang,B.;Fan,A.P.*; Cai,S*.Preparation and applications of a chemiluminescent filmdeposited on a well plate: focusing on 96-well technology,Analytical Chemistry,2025, 97, 13619-13627.
2.Wang, F.Q.; Sun, Y.N.; Jin, M.Z.; Zhang, B.X.; Cui, Y.W.; Kong, D.X.; Li, D.M.; Yan, X.L.;Fan, AP*. Rational design to improve the detection sensitivity of sandwich-type lateral flow immunoassays, AnalyticalMethods, 2025, 17, 3517.
3.Yan, X.L.;Wang, J.N.; Yang, L.; Jiang, P.Y.; He, Y.; Wang, W.;Fan, A.P.; Cao, Z.J.; Zheng, X.J.; Ai, F.R.;Guo, L.*Hierarchical CoZn-MOF-supported Agnanocatalyst forchemiluminescenceassay,ACS Applied Nano Materials, 2025, 8,21551-21561.
4.Guo, K.Y.;Xiao, Y.P.;He, Y.;Liu, J.;Guo, L.;Fan, A.P.; Zeng, Z.L.; Zheng, X.J.; Yan, X.L.*Ultra-convenient and rapid synthesis of FeAg MOGs for sensitive test strips detection of dopamine in human serum,Microchimica Acta,2025, 192,702.
5.Liang, R. S.; Wang, F.; Li, S. S; Niu, Y. J.; Sun, Y. N.;Hong, S. L.;Fan, A. P.*,A sensitive gold nanoflower-based lateral flow assay coupled with gold staining technique for the detection of SARS-CoV-2 antigen, Microchimica Acta, 2024, 191, 7: 434.
6.Liang, R. S.;Fan, A. P.*; Wang, F. Q.; Niu, Y. J.*, Optical lateral flow assays in early diagnosis of SARS-CoV-2 infection,Analytical Sciences, 2024, 40, 9: 1571-1591.
7.Li, M. L.; Yu, Y. F.; Li, S. S.; Wang, F. Q.; Hong, S. L.; Sun, Y. N.;Fan, A. P.*,A simple chemiluminescent method for the quantification of exosomes based on horseradish peroxidase adsorbed on two-dimensional nanomaterials, Talanta, 2024, 275, 126156.
8.Zhang, Y. Y.; Li, M. L.; Li, S. S;Fan, A. P.*, Two-dimensional metal-organic framework catalyzed chemiluminescent reaction for alpha-glucosidase inhibitor screening,Talanta, 2023, 124748.
9.Yu, Y. F; Wang, R. Y.; Li, M. L.; Li, S. S.;Fan, A. P.*, Preparation and application of graphene oxide nanocomposites loaded with enzymes and liposomes, Carbon Letters, 2023, 1045-1055.
10.Zhang, Y. Y.; Li, S. S.; Liang, R. S.; Li, M. L.; Wang, F. Q.;Fan, A. P.*, A turn-on chemiluminescent assay for alkaline phosphatase using two-dimensional Fe-centered metal-organic frameworks as the signaling probe,Analytical Sciences, 2023, 1541–1550.
11.Li, D. M.; Liang, R. S.;Fan, A. P.*, Ultrasensitive colorimetric detection of tetracyclines based on in-situ growth of gold nanoflowers, Analytical Sciences, 2023, 1223–1231.
12.Liu, C; Zhang, Y.Y.; Wang, P.H.;Fan, A.P.*. Enhancement effect of 2,3-dimethyl maleic acid on luminol chemiluminescence reactions and its application in detection of sequence-specific DNA related to hepatitis B virus, Talanta,2022,250, 123724.
13.Wang, P.H.; Yue, N.N.; Liu, C.;Fan, A.P.*. Colorimetric assay for tetracyclines based on europium ion-induced aggregation of gold nanoparticles,Analytical Sciences,2022, 38, 8, 1073-1081.
14.Liu, F.; Zhu, J.D.; Dai, P.P.; Deng, J.; Qin, J.; Yuchi, Z.G.;Fan, A.P.; Wang, Z.; Zhao, Y.J.,Double-lock nanomedicines enable tumor-microenvironment-responsive selective antitumor therapy, Advanced Functional Materials, 2021, 31,2009157.
15.Yue, N.N.; Li, D.M.;Fan, A.P.*. A Simple colorimetric analytical assay for the determination of tetracyclines based on in-situ generation of gold nanoparticles coupling with a gold staining technique,Analytical Sciences, 2021, 37, 11, 1583.
16.Wang, R.Y.; Yue, N.N.;Fan, A.P.*. Nanomaterial-enhanced chemiluminescence reactions and their applications, Analyst, 2020, 145, 23, 7488-7510.
17.Li, Y.; Wang, R.Y.;Fan, A.P.*. Gold Nanocluster-catalyzed Luminol Chemiluminescent Sensing Method for Sensitive and Selective Detection of Alkaline Phosphatase, Analytical Sciences, 2020, 36, 9, 1075-1079.
18.Yang, N.; Huang, Y. X.; Ding, G. S.;Fan, A. P.*, In situ generation of prussian blue with potassium ferrocyanide to improve the sensitivity of chemiluminescence immunoassay using magnetic nanoparticles as label, Analytical Chemistry, 2019, 91, 4906-4912.
19.Yang, H. L.; Huang, Y. X.; Zhao, Y. J.;Fan, A. P.*; Sensitive chemiluminescent sensing method for mercury(II) ions based on monolayer molybdenum disulfide, Analytical Sciences, 2019, 35, 551-556.
20.Wang, M. L.; Kong, Y. F.; Li, Y.; Huang, Y. X.;Fan, A. P.*, A chemiluminescence method for the determination of mercury(II) ions by tuning the catalytic activity of gold nanoparticles with ethylenediamine, Analytical Methods, 2019, 11, 1317-1323.
21.An Y.; Zhu, J. D.; Liu, F.; Deng, J.; Meng, X.; Liu, G. Q.; Wu, H. Y.;Fan, A. P.; Wang, Z.; Zhao, Y. J.*, Boosting the Ferroptotic Antitumor Efficacy via Site-Specific Amplification of Tailored Lipid Peroxidation, ACS Applied Materials & Interfaces, 2019, 11, 29655-29666.
22.Wang, Y.; Wang, M. L.; Han, L.; Zhao, Y. J.;Fan, A. P.*, Enhancement effect of p-iodophenol on gold nanoparticle-catalyzed chemiluminescence and its applications in detection of thiols and guanidine, Talanta, 2018，182, 523-528.
23.Han, L.; Li, Y.;Fan, A. P.*, Improvement of mimetic peroxidase activity of gold nanoclusters on the luminol chemiluminescence reaction by surface modification with ethanediamine, Luminescence, 2018, 33, 751-758.
24.Li, J.; Meng, X.; Deng, J.; Lu, D.; Zhang, X.; Chen, Y.; Zhu, J. D.;Fan, A. P.; Ding, D.; Kong, D. L.; Wang, Z.; Zhao, Y. J.*, Multifunctional micelles dually responsive to hypoxia and singlet oxygen: enhanced photodynamic therapy via interactively triggered photosensitizer delivery, ACS Applied Materials & Interfaces, 2018,10, 17117-17128.
25.Yao, L. Y.; Yu, X. Q.; Zhao, Y. J.;Fan, A. P.*,Label-free chemiluminescent strategy for highly selective and sensitive detection of adenosine triphosphate by cofactor-dependent enzymatic ligation-triggered polymerase chain reaction, Sensors and Actuators B-Chemical, 2017, 238, 175-181.
26.Sheng, Y. Y.; Yang, H. L.; Wang, Y.; Han, L.; Zhao, Y. J.;Fan, A. P.*,Silver nanoclusters-catalyzed luminol chemiluminescence for hydrogen peroxide and uric acid detection, Talanta, 2017, 166, 268-274.
27.Dong, X. P.; Guo, X. L.; Liu, G. Q.;Fan, A. P.; Wang, Z.; Zhao, Y. J., When self-assembly meets topology: an enhanced micelle stability, Chemical Communications, 2017, 53, 3822-3825.
28.Yu, X. Q.; Sheng, Y. Y.; Zhao, Y. J.;Fan, A. P.*, Employment of bromophenol red and bovine serum albumin as luminol signal co-enhancer in chemiluminescent detection of sequence-specific DNA, Talanta, 2016, 264-271.
29.Yu, D. L.; Wang, P.; Zhao, Y. J.;Fan, A. P.*, Iodophenol blue-enhanced luminol chemiluminescence and its application to hydrogen peroxide and glucose detection, Talanta, 2016, 655-661.
30.Zhang, H. H.; Yao, L. Y.; Yu, X. Q.; Zhao, Y. J.;Fan, A. P.*, Graphene oxide-based chemiluminescent sensing platform for label-free detection of trypsin and its inhibitors, Analytical Methods, 2015, 9949-9956.
31.Yao, L. Y.; Yu, X. Q.; Zhao, Y. J.;Fan, A. P.*, An aptamer-based chemiluminescence method for ultrasensitive detection of platelet-derived growth factor by cascade amplification combining rolling circle amplification with hydroxylamine-enlarged gold nanoparticles, Analytical Methods, 2015, 8786-8792.
32.Zhang, H. H.; Yu, D. L.; Zhao, Y. J.;Fan, A. P.*, Turn-on chemiluminescent sensing platform for label-free protease detection using streptavidin-modified magnetic beads, Biosens. Bioelectron., 2014, 61, 45-50.
33.Song, Y. H.; Yang, X.; Li, Z. Q.; Zhao, Y. J.;Fan, A. P.*, Label-free chemiluminescent ATP aptasensor based on graphene oxide and an instantaneous derivatization of guanine bases,Biosens. Bioelectron., 2014,51, 232-237.
34.Wang, P.; Zhang, T. H.; Yang, T. Y.; Jin, N.; Zhao, Y. J.;Fan, A. P.*;A cascade amplification strategy based on rolling circle amplification and hydroxylamine amplified gold nanoparticles enables chemiluminescence detection of adenosine triphosphate, Analyst, 2014, 139, 3796-3803.
35.Wang, Z.; Chen, C.; Liu, R. H.;Fan, A. P.; Kong, D. L.; Zhao, Y. J., Two birds with one stone: dendrimer surface engineering enables tunable periphery hydrophobicity and rapid endosomal escape, Chemical Communications, 2014, 50, 14025-14028.
36.Song, Y. H.; Yang, T. Y.; Zhang, T. H.; Jin N.; Zhao, Y. J.;Fan, A. P. *, Ultrasensitive chemiluminescent immunoassay labeled with graphene oxide, Anal. Methods,2013, 5, 3646-3649.
37.Niu, Y. J.; Wang, P.; Zhao, Y. J.;Fan, A. P.*,Turn-on colorimetric sensor for ultrasensitive detection of thrombin using fibrinogen-gold nanoparticle conjugate,Analyst,2013, 138, 1475-1482.
38.Wang, P.; Song, Y. H.; Zhao, Y. J.;Fan, A. P.*, Hydroxylamine amplified gold nanoparticle-based aptameric system for the highly selective and sensitive detection of platelet-derived growth factor,Talanta, 2013, 103, 392-397.
39.Zhang, J.; Sun, M.;Fan, A. P.; Wang, Z.; Zhao, Y. J.*,The effect of solute-membrane interaction on solute permeation under supersaturated conditions, Int. J. Pharm., 2013, 441, 389-394.
40.Song, M. J.;Fan, A. P.; Wang, Z.; Zhao, Y. J.*, Dendrimer-mediated drug delivery to the skin, Soft Matter, 2012, 8, 4301-4305.
41.Niu, Y. J.; Zhao, Y. J.;Fan, A. P.*,Conformational switching immobilized hairpin DNA probes following subsequent expanding of gold nanoparticles enables visual detecting sequence-specific DNA,Anal. Chem., 2011, 83, 7500-7506.
42.Fan, A. P.; Lau, C. W.; Lu, J. Z., Direct colorimetric visualization of mercury (Hg2+) based on the formation of gold nanoparticles, Talanta, 2010, 82, 687-692.
43.Fan, A. P.; Lau, C. W.; Lu, J. Z., Hydroxylamine-amplified gold nanoparticles for the homogeneous detection of sequence-specific DNA, Analyst, 2010, 135, 1400-1405. Fan, A. P.; Cao, Z. J.; Li, H.; Kai, M.; Lu, J. Z., Chemiluminescence platforms in immunoassay and DNA analyses, Anal. Sci., 2009, 25, 587-597.
44.Fan, A. P.; Lau, C. W.; Lu, J. Z., Hydroxylamine-amplified gold nanoparticles for the naked eye and chemiluminescent detection of sequence-specific DNA with notable potential for single-nucleotide polymorphism discrimination, Analyst, 2009, 134, 497-503.
45.Fan, A. P.; Lau, C. W.; Lu, J. Z., Colloidal gold-polystyrene beads hybrid for chemiluminescent detection of sequence-specific DNA, Analyst, 2008, 133, 219-225.
46.Fan, A. P.; Lau, C. W.; Liao, Z. X.; Liang, J. Y.; Lu, J. Z., A novel chemiluminescence metalloimmunoassay based on gold label, Chinese J. Anal. Chem., 2006, 34, 35-37.
47.Fan, A. P.; Lau, C. W.; Lu, J. Z. Magnetic bead-based chemiluminescent metalimmunoassay with a colloidal gold label, Anal. Chem., 2005, 77, 3238-3242.
专利
(1)樊爱萍;孙溢锘;周鹏赟;一种定量检测外泌体的比色方法,中国, 2026100804335 (已受理)
(2)樊爱萍;杨洪丽;于晓倩;三种乳癌肿瘤标志物同时检测的方法,中国，ZL201711042462.X (已授权)
(3)樊爱萍;孔亚访;王影;韩璐;于晓倩;生营营;粒径可控的水化纳米碗烯制备方法,中国, ZL201610993702.3 (已授权)
(4)樊爱萍;于晓倩;姚璐妍;鲁米诺-过氧化氢-溴酚红-HRP-BSA化学发光体系检测HRP的方法,中国, 2015101734219 (已授权)
